*executive function is how to manage time, pay attention, switching focus, plan and organize, remember detail, avoid saying or doing the wrong thing, do things based on your experience
There is a blood test used to detect cryoglobulinemia, but it is important that the blood sample is kept at room temperature and handled carefully. Even though the markers for cryoglobulinemia are common in people infected with the hepatitis C virus, many people with hepatitis C do not have the symptoms or disorders associated with it.
The symptoms and disorders associated with cryoglobulinemia can be mild, moderate or severe. Symptoms of cryoglobulinemia include red or purple blotching skin and joint and generalized pain. Cryoglobulinemia can affect the skin, kidneys, nerves and joints. Conditions associated with cryoglobulinemia include vasculitis (inflammation of the blood vessels), peripheral neuropathy, Reynaudís Phenomenon (hands that are sensitive to cold temperature and turn white, red, blue), and Non-Hodgkinís lymphoma (cancer of the lymphatic tissues). Treating cryoglobulinemia consists of treatment of the underlying disease (hepatitis C) as well as the administration of medications to suppress the immune system, and plasmapheresis (blood is taken from the body, filtered and returned to the body). Treating the underlying cause (hepatitis C) resolves or improves this condition. Recent studies have found that treating hepatitis C with direct-acting antiviral medications are safe and effective to treat cryoglobulinemia.
Increased prevalence of ITP occurs in people with HCV.
One study found that 15.3% of people with HCV had PN. Treatment consists of treating the underlying disease (HCV) to prevent further damage. The damage of PN seldom is reversed. It is helpful to avoid any substances (medications, alcohol, certain herbs/supplements) that cause or make it worse. Other infections that can cause PN include diabetes, HIV, Lyme disease, shingles, and Epstein-Barr.
PCT can also cause skin discoloration, either darkening or lightening of the skin, increased facial hair, thickening of the skin, and alopecia (hair loss). Treatment of PCT can involve phlebotomy, dietary iron restriction, reducing alcohol consumption, avoiding exposure to the sun or the use of sunscreen, and avoiding or minimizing estrogen exposure.
Symptoms include purpura (discoloration of the skin caused by bleeding vessels) petechiae, (pinpoint red rash caused by minor hemorrhaging), and usually affects the lower extremities of the body. Other symptoms include fever, itching welts, muscle aches and pain, enlarged lymph nodes as well as peripheral neuropathy. Treatment consists of treating the underlying cause (HCV) with direct-acting antiviral medications with good results.
Other treatment options include the use of immunosuppressive drugs. Vasculitis can also affect other organs such as the kidneys, liver, lungs, heart and central nervous system, but this is uncommon. A skin biopsy that shows inflammation of the small blood vessels indicates vasculitis. Another type of vasculitis, leukocytoclastic vasculitis, is also associated with hepatitis C. An uncommon condition.