Best Probiotic Supplements Of 2022 : Top Probiotics For Gut Health


Best Probiotic Supplements Of 2022 : Top Probiotics For Gut Health

There is a significant increase in healthy habits. Many people are learning the importance of specific microbes and how probiotics help their growth. However, some find it challenging to get the best probiotics. Although individuals know these supplements, they are unaware of the different types that exist, which is confusing.

Various probiotic brands have distinct qualities besides the strains they contain. They are mainly classified as supplements, so the ingredients and dosage forms are essential. We reviewed the different brands based on vital features and provided the top five in this article.  Later in this article, we will discuss them and show their selling points.

Best 5 Probiotic For Health Related Issues In 2022

Now that you understand the standards and criteria we used for this review. Here is our list of the five best probiotics in the market.

  1. Oweli Probiotic – Overall Best Probiotic For Intestinal Health
  2. Garden of Life  – Top Formula for Women’s Health
  3. Culturelle Probiotic – Vegetarian Formula For the Digestive System
  4. Seed DS-01 Probiotic – Preferred Synbiotic Technology With Micronutrients
  5. Lovebug Yeast is a Beast – Yeast Formula For Urinary Tract and Vaginal Health

#1. Oweli Probiotic – Overall Best Probiotic For Intestinal Health

The Oweli brand is an advanced multiple strain formula containing four powerful probiotic microbes, giving it a broader spectrum of activities and functions. Each bottle of these probiotics has 60 capsules, with each capsule having a 20 billion CFU potency. The required daily dose for this supplement is two pills since 40 billion CFU provides the required impact.

Oweli is our top pick because the company shows a solid commitment to product safety. They have a GMP-compliant facility approved by the Food and Drug Administration (FDA) and conduct appropriate lab tests. Besides that, they have various customer reviews to back up the claims of effectiveness. Besides these, the manufacturer offers other benefits and incentives, including a 15% discount when you sign up, alongside a 100-day bottom-of-the-bottle guarantee.


MAKtrek® Bi-Pass Technology:

Oweli Probiotic is a proprietary blend using MAKtrek® Bi-Pass Technology delivery system for better efficiency. It enables the live-cultured microorganisms to survive in gastric acid instead of being destroyed. That way, they can get into the intestines, where these microbes carry out their functions.

Intestinal Health: We understand that promoting gut health is a general claim for most probiotics or yogurt-related foods. However, Oweli goes beyond merely nourishing you with good bacteria and replenishing normal flora. The combination of strains and other herbal ingredients provides excellent digestive support and promotes optimal bowel movement.

Weight Management: The Oweli probiotic may help in weight management. Besides supporting digestion, it helps you feel fuller and can encourage proper food portioning. The Lactobacillus content also reduces lipid absorption in the body. That means it stores less fat and uses up calories more efficiently due to its effects on metabolism.

Immune Response: The constant supply of beneficial bacteria to the body reduces or slows the growth of the harmful ones. That, in turn, rids the body of potential infections and helps build the immune system. Studies show that probiotics help increase the production of the body’s natural antibodies. Thus, it is also easier for the cells to fight against illness.

Skin Health and Mood Support: Another great benefit of the Oweli probiotic is that it promotes healthy skin. This effect results from the balance of microflora that the supplement achieves by increasing the number of helpful organisms. Similarly, it also promotes good moods by reducing stress and anxiety levels. Some researchers claim it is a result of gut bacteria activity.


  • It contains a multi-strain formula
  • Made in CGMP-compliant facility and lab-tested
  • Provides a wide range of health benefits
  • 100-day money-back guarantee
  • Made with natural ingredients
  • Cost-effective and allows various payment platforms
  • No calories and added sugars


  • Only on direct order from their website
  • Requires taking two capsules daily with food

=> Click here to visit the official website of Oweli Probiotic

#2. Garden of Life – Top Formula for Women’s Health

The Garden of Life Dr. Formulated Probiotic is specially made for women because it significantly impacts vaginal health. It contains 16 strains of microbes, including some rare ones like Lactobacillus fermentum. Each package has 30 vegetarian capsules with a dosage of 50 billion CFU. This supplement’s advantage over others is that you can take it with or without food.

Furthermore, this brand of probiotics has unique reasons ensuring its position in our list of preferred probiotics.  One significant reason is that a human microbiome and nutrition expert doctor created the formula. Generally, Garden of Life products is eco-friendly as they are the first supplement company to be carbon-free certified.


Supports Women’s Health: The main selling point for the Garden of Life brand is its role in supporting women’s health. Lactobacillus fermentum is beneficial for specific issues peculiar to women, as with other strains of a similar genus. This brand of probiotics helps combat vaginal infections such as yeast and urinary tract infections. They promote the presence of normal flora and create a balance.

Immune and Digestive Health: Another unique feature of this probiotic is its effect on some essential body systems. The various microbial strains work in synergy to ensure an improved immune response. Thus, boosting the ability to fight specific infections. Like many other supplements in this class, it also affects digestive health and may even relieve constipation.

Shelf Stability: The Garden of Life probiotic has excellent shelf quality. That means it can last for a specified time without any tasking storage measures and retains its quality. As long as you keep the product away from direct heat or other extreme conditions, it stays potent till the expiry date. That means this brand of probiotics should not be refrigerated.

Prebiotic Fiber Blend: Besides the 16 strains, Garden of Life probiotics for women also contains an organic whole food prebiotic fibre blend. It consists of organic potato, resistant starch, and acacia fibre. These contribute significantly to the digestive health benefits of this product and may account for its activity against constipation.

Natural and Gluten-free: The Garden of Life probiotics have no carriers, fillers, flavors, sweeteners, artificial colors, or preservatives. Instead, it contains organic ingredients that make this probiotic suitable for vegans. It is gluten-free and does not contain familiar allergens sources like soy and dairy products. Therefore, many people can use the product without worrying about the side effects and allergic reactions.


  • No refrigeration required
  • It does not contain gluten and allergens like dairy or soy
  • Supports vaginal health
  • Non-GMO containing
  • Vegetarian-friendly capsules
  • Has replacement or refund eligibility
  • All-natural ingredients
  • Contains prebiotic fiber blend


  • Shipped only within the country and to select places
  • Availability in various sales outlets causing slightly different pricing

=> Click here to visit the official website of Garden Of Life

#3. Culturelle Probiotic – Vegetarian Formula For the Digestive System

Culturelle is a top-notch clinically studied and tested probiotic with 10 billion CFU of only one potent Lactobacillus strain. It has a specific use and provides targeted benefits to users. Each bottle contains 30 vegetarian capsules. The recommended dosage is one capsule daily. It is also a highly-recommended brand by doctors and pharmacists all over the US.

Culturelle also supports the immune system and aids its defense against infections that cause specific diseases. Meanwhile, this probiotic also has an advantage because it contains organic ingredients without allergens like dairy and soy.


Contains Inulin: We cannot ignore the presence of chicory root extract in this probiotic brand, mainly because of its benefits. It has a prebiotic fiber called inulin, responsible for several effects, including replacing normal gut flora. It also reduces inflammation and promotes the absorption of minerals, which contributes to digestion.

Reduces Digestive Problems: Though many other probiotics affect the gut, Culturelle helps reduce issues like excess gas, bloating, and diarrhea. The microbe strain primarily impacts the stomach and intestinal health. It also restores the natural balance of microbes in the body and enhances digestion.

Purity and Potency Guarantee: Numerous customer reviews back up this brand’s claims of effectiveness. Besides those, the supplement has a guaranteed potency until the date of expiry if you store the product as directed. Culturelle also contains the most clinically researched strain of probiotics globally, Lactobacillus rhamnosus. 

Organic Ingredients: Culturelle probiotic uses organic ingredients like chicory root extract, maltodextrin, and others. It is also GMO-free, suitable for vegans and people with specific dietary restrictions. This brand is gluten-free and does not contain gelatin or filler substances. That increases the natural balance and safety profile, so almost anyone can use it.


  • Works on specific digestive issues
  • No added sugars
  • Vegetarian-friendly formula
  • No gluten, gelatin, soy, or dairy
  • It contains a prebiotic–inulin
  • Purity and potency guaranteed


  • Contains artificial color
  • Has only one microbial strain

=> Click here to visit the official website of Culturelle Probiotic

#4. Seed DS-01 Probiotic – Preferred Synbiotic Technology With Micronutrients

The Seed DS-01 Probiotic contains about 24 strains of probiotics and 53.6 billion AFU (Active Fluorescent Units) per capsule with a unique delivery technology. This brand goes through various lab-testing processes to ensure quality. It is the go-to supplement for gastrointestinal health, amongst other benefits.

Seed Synbiotic has a guaranteed shelf life of about a year. The brand is climate-friendly and promotes environmental sustainability. It is also gluten-free and has no preservatives, binders, soy, meat, dairy, or nuts. There is a risk-free guarantee on any purchase for up to 30 days, especially if you order on the company website.


ViaCap® Delivery Technology: This brand uses the ViaCap® Delivery Technology, which works on a 2-in-1 formation. It involves a capsule-in-capsule design that shields against digestive enzymes and ensures the probiotics get to the intestines. Hence, we can vouch that the microbes remain viable for delivery till it reaches the site of action.

Green Packaging and Refill System: The Seed brand is climate-friendly and ensures its brand reflects that. Thus, they have a sustainable refill system that benefits you and your environment. For example, the welcome kit has a smaller vial for travel. The monthly refill package is a compostable biofilm material. This feature shows a commendable commitment to a green earth.

Broad Spectrum of Effects: Seed DS-01 Synbiotic contains 24 strains of multiple species of probiotics, which increases the range of activities in the body.  You can gain more from the product than just stabilizing the gastrointestinal tract. It enhances and balances cardiovascular, immune systems, and skin health.

Micronutrient and Prebiotic Formulation: The Seed DS-01 probiotic outer capsule contains 400mg of the Indian Pomegranate whole fruit extract. That provides about 40% of polyphenolic and phenolic bioactive substances. The microbes in the gut transform these compounds into active metabolites that produce specific effects that impact general human health.


  • Boosts gastrointestinal health
  • Uses a specific delivery technology
  • Portable package with an easy refill system
  • Contains micronutrients
  • Free shipping in the United States
  • 30-day guarantee


  • Requires taking two capsules on an empty stomach
  • Sold on a subscription basis from the company

=> Click here to visit the official website of Seed Probiotic

#5. Lovebug Yeast is a Beast – Yeast Formula For Urinary Tract and Vaginal Health

The Lovebug Probiotic is a yeast formula made of Lactobacillus species to support women’s health needs. It contains 50 billion CFU from five different targeted microbial strains at production. It is excellent for people prone to infections, and some even claim to help restore vaginal pH balance.

The supplement is produced in the United States of America in a GMP-compliant facility and has a recommended dose of one capsule daily. Besides the probiotics, other ingredients in this supplement are magnesium stearate, cellulose, hypromellose, silica, and gellan gum. It is free from the eight major allergens. Rest assured, it is non-GMO, with no artificial flavors and colors. You can get more information on the product by visiting its official website.


Urinary Tract and Vaginal Health: The Lactobacillus strains fight against yeast infections like candida and prevent recurrent UTI in women. Thus, it gives the much-needed vaginal support and is mild enough for daily use. The Lovebug “Yeast is a Beast” probiotic promotes a healthy pH balance, especially after increased acidity to fight unwanted microbes.

Contains Cranberry Fruit Powder: This probiotic brand contains the Pacran formulation, a widely-researched cranberry fruit extract. We aptly call it a superfood because of the numerous health benefits it provides. It also includes vitamins, antioxidants. Other constituents of this supplement are phenols and other substances that studies proved to promote cardiovascular and urinary tract health. It also has a positive impact on the gastrointestinal tract.

Assured Purity: The ingredients used in formulating this product are pure.  The brand is committed to consumer safety and has received the Eco-Excellence and Product of the Year awards. They are also manufactured in a GMP-registered facility that complies with FDA-given standards.

Line of Similar Specific Probiotics: Besides the “Yeast is a Beast ” product, the Lovebug brand also has a line of similar probiotics that caters to various individuals, including kids. There are also products for immunity boost and skinny or slim people. Therefore, everyone can benefit from its products. These supplements also undergo third-party testing and other standard procedures.


  • With cranberry fruit extract
  • Has shelf stability
  • Free from major allergens
  • No GMO or artificial flavors and colors
  • Promotes vaginal health and balanced pH


  • The bottle is glass and may not survive bad handling
  • Large capsules

=> Click here to visit the official website of Lovebug Yeast

How We Made This List For Best Supplements 

We gathered and evaluated over ten of the most widely-used probiotics in the market to write this review. Though popularity was a common factor, we looked at other essential characteristics for all the supplements. Those features provided the standards that formed our guidelines for examining and comparing the different brands.

What We Looked For

  • The Microbe Strain: The strain is the first significant probiotic feature. So, it is essential to know the genus and species of organisms used. Additionally, it is vital as a form of identity because that decides the specific health effect of the product. We ensured that each brand we chose had the appropriate strain marker and was on the FDA-approved list of bacteria.
  • Probiotic Safety: Like other supplements, the best probiotics must be safe and pure. These considerations rank highly because of the nature of such products and the health hazards they pose. Therefore, we ensured that the products we chose had no history of infections or other unwanted metabolic reactions.
  • Health Claims: It’s typical for overzealous brands to print uses and benefits that their products do not have. Usually, health organizations permit only general claims, except for cases with sufficient scientific evidence. In picking the best probiotics, we ensured that they had no misleading information and didn’t make false claims merely to attract customers.
  • Effectiveness: Probiotics must contain a considerable dose of the organism to produce the required reactions. Generally, we measure the adequate amount per gram in colony-forming units (CFU). The minimum a good brand should contain is 10⁶ (one million). All the chosen products have at least one billion (10⁹) CFU for this review, so they survive digestive processes for the desired effects.
  • Brand Reputation: A brand’s reputation is vital and consists primarily of what people say about them. That includes their general customer service ratings and reviews on their products. Again, it also involves their ethics and measures to ensure quality. We confirmed that our list of brands engages in the proper production and sales practices.

Buying Guide: Recommended By Experts

Besides the cost, there are several things to look out for to choose the right probiotic for you. You mustn’t pick one randomly without conducting the appropriate research. One of the first steps to take is consulting your physician. That is vital, especially if you have a chronic health condition or use any medications. We will discuss some other factors you must consider.

  • Personal Health Needs

You must consider your current personal health needs before buying this supplement. The reason is that some of these products are specific and target a set of individuals and needs. For example, a man would not need a probiotic specified for promoting vaginal health.

  • Ingredients

Another feature you should pay close attention to is the ingredients in the supplement besides the microbial species. Usually, you can tell a product’s quality from the contents because the organic ones are better. Check if they have artificial colors, flavors, and other fillers. It will help if you look out for any possible allergens like soy, nuts, and dairy.

  • Shelf-life Conditions

The required storage condition of the probiotic is also essential. It is always better to go for shelf-stable brands because they are easier to store.

  • Customer Service and Reviews

Generally, it is advisable to patronize brands with excellent customer service, which shows that they prioritize your needs and safety. 

 It is also customary to go through the reviews left by other customers who bought or used that probiotic. It will give you an idea of what it offers.

Frequently Asked Questions On Probiotics

  1. What is the most effective or best probiotic?

Several brands of probiotics are available in the market, and many of them are great. However, picking one depends on various factors, primarily your health needs and the results you want. We highlighted the top five picks after a lengthy evaluation process for this review. They include Oweli, Garden of Life, Culturelle, Seed Synbiotic, and Lovebug.

  1. What signs show that you need probiotics?

Probiotics are not for the treatment of any specific ailments but can help to produce certain effects. So, various signs may warrant using this supplement. Some of them are bloating, diarrhea, constipation, frequent infections, skin issues, or after taking antibiotics.

  1. Should you take probiotics every day?

As mentioned earlier, probiotics do not treat any specific illness. They are natural supplements that may help as an adjunct in some cases or to boost your health in other cases. Therefore, it is safe to take them every day, which is the frequency doctors prescribe. Nevertheless, you may also decide to stop for a while, especially if you need to take other medications.

  1. What should I look for when buying probiotics?

It is essential to analyze a probiotic before buying it. There are specific things to note. Look out for the expiry date to ensure it is safe to use. Also, check to ensure you are not allergic to any ingredients. Make sure the product can meet your health needs, and you can store it without difficulty.

Conclusion: Improve Your Health & Gut Health Today

Probiotics are essential but delicate supplements and require careful consideration. Ensure that you pay attention to all the details for maximum benefit. Our review shows you the top five brands in the market currently. Ultimately, you can find one that suits you from this shortlist.


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